Mouse Apolipoprotein D (APOD) ELISA Kit

Este producto es parte de APOD - Apolipoprotein D
Mouse Apolipoprotein D (APOD) ELISA Kit
715€ (96 tests)

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Name
Mouse Apolipoprotein D (APOD) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx519622
Tested Applications
ELISA

Description

Mouse Apolipoprotein D (APOD) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Apolipoprotein D concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
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Data sheet
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Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Apolipoprotein D (APOD)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
78 pg/ml - 5000 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P51910
Alias
APOD, Apod, apolipoprotein D
Background
Elisa Kits for: APOD
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Apolipoprotein D (APOD) is a unique member of the apolipoprotein family, functioning as a lipid transporter in the plasma and extracellular fluids. Unlike other apolipoproteins, APOD is not synthesized in the liver but is predominantly produced in the central nervous system (CNS), liver, kidneys, and mammary glands. APOD associates with high-density lipoprotein (HDL) and contributes to cholesterol transport, as well as lipid metabolism. Structurally, APOD is classified as a member of the lipocalin family, which binds small hydrophobic molecules, such as arachidonic acid and cholesterol. It has a prominent role in antioxidant defense by neutralizing reactive oxygen species (ROS) and reducing oxidative stress, particularly in the CNS. APOD is upregulated during injury and neurodegenerative conditions, including Alzheimer’s disease, Parkinson’s disease, and stroke, indicating its neuroprotective function. Elevated levels of APOD are also found in cancer, cardiovascular disease, and diabetes, suggesting its role in cellular stress responses. APOD may regulate inflammation, cellular lipid homeostasis, and signal transduction, making it a promising biomarker and therapeutic target in age-related disorders, metabolic syndromes, and neurological diseases.

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