Mouse Coronin-7 (CORO7) ELISA Kit
715€ (96 tests)
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name
Mouse Coronin-7 (CORO7) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx508057
tested applications
ELISA
Description
Mouse Coronin-7 (CORO7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Coronin-7 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Coronin-7 (CORO7) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9D2V7 |
| Gene ID | 78885 |
| Alias | CRN7,POD1,70 kDa WD repeat tumor rejection antigen homolog,Coronin-7 |
| Background | Elisa Kits for: CORO7 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Coronin 7 (CORO7) is a member of the coronin protein family, distinguished by its lack of actin-binding capability, unlike other coronins. Instead, it functions as an F-actin regulator involved in directing anterograde transport from the Golgi apparatus to endosomes. CORO7 localizes to the trans-Golgi network and is essential for maintaining Golgi apparatus morphology. Its recruitment to Golgi membranes requires Src kinase activity and the integrity of the AP-1 adaptor protein complex. CORO7 interacts with the μ1-subunit of AP-1 via a tyrosine-288-based sorting signal and is phosphorylated by Src kinase, which is crucial for its membrane targeting. Additionally, CORO7 undergoes K33-linked polyubiquitination via an E3 ligase complex, influencing its function in Golgi trafficking. Notably, CORO7 does not interact with actin or participate in actin-mediated processes but plays a significant role in vesicular trafficking pathways.
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