Mouse Interferon Alpha 4 (IFNa4) Protein
260€ (10 µg)
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name
Mouse Interferon Alpha 4 (IFNa4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067332
tested applications
WB, SDS-PAGE
Description
Mouse Interferon Alpha 4 (IFNa4) protein is a recombinant protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interferon Alpha 4 (IFNa4) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Asp26-Lys186 Tag: N-terminal His tag |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 20.2 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07351 |
| Alias | INFA4,IFN-alpha4a,IFN-alpha-4,Interferon alpha-4B,Interferon alpha-76,Interferon alpha-M1 |
| Background | Protein IFNA4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Endotoxin Level: < 1.0 EU per 1 µg (determined by the LAL method) Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
Interferon Alpha 4 (IFNA4) is another member of the type I interferon family that contributes to the antiviral immune response. While less characterized than IFNA1 and IFNA2, IFNA4 exhibits similar functional properties, including activation of the IFNAR pathway and induction of interferon-stimulated genes that inhibit viral replication and modulate the immune response. Studies suggest that IFNA4 may have unique regulatory functions or tissue-specific roles within the broader interferon response. Its expression and functional significance may vary depending on the type of infection or immune challenge. As with other type I interferons, IFNA4's dysregulation could contribute to autoimmune conditions, and understanding its precise role in health and disease remains an area of ongoing research.
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