Mouse Interleukin 1 Receptor Type 2 (IL1R2) Protein
546€ (100 µg)
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935106861
info@markelab.com
name
Mouse Interleukin 1 Receptor Type 2 (IL1R2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx620389
tested applications
ELISA, WB, SDS-PAGE
Description
Mouse Interleukin 1 Receptor Type 2 (IL1R2) Protein is a recombinant Mouse protein produced in a Mammalian cell expression system.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 1 Receptor Type 2 (IL1R2) |
| Host | Mammalian cells |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 40.45 kDa Sequence Fragment: Met1-Glu355 Tag: C-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized Reconstitute in sterile water to produce a stock solution. |
| Tested Applications | ELISA, WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | P27931 |
| Alias | IL1R2,CD121d. IL1 RII |
| Background | Protein IL1R2 |
| Note | This product is for research use only. This product is shipped with ice packs. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2(membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
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