Mouse Interleukin 21 (IL21) Protein
234€ (10 µg)
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name
Mouse Interleukin 21 (IL21) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168451
tested applications
WB, SDS-PAGE
Description
Mouse Interleukin 21 Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 21 (IL21) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Pro25-Ser146 Tag: N-terminal His tag and GST tag |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 47.5 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9ES17 |
| Alias | Za11,IL-21,CVID11 |
| Background | Protein IL21 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
Interleukin 21 (IL21) is a potent cytokine produced primarily by activated CD4+ T cells, particularly T follicular helper (Tfh) cells and T helper 17 (Th17) cells. It belongs to the type I cytokine family and plays a critical role in regulating both innate and adaptive immune responses. IL-21 acts on a variety of immune cells, including B cells, T cells, natural killer (NK) cells, and dendritic cells (DCs), modulating their proliferation, differentiation, and functional activities. Its broad immunomodulatory effects make it a key regulator of immune homeostasis, inflammation, and host defense against pathogens and tumors. IL-21 is crucial for the development of germinal centers and the production of high-affinity antibodies, particularly through its regulation of B cell differentiation and antibody class switching. It also plays a significant role in promoting the cytotoxic activity of NK cells and CD8+ T cells, which are essential for anti-tumor and antiviral immunity
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