Mouse Macrophage-stimulating protein receptor (MST1R) ELISA Kit

Este producto es parte de MST1R - macrophage stimulating 1 receptor
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Macrophage-stimulating protein receptor (MST1R) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx389794
tested applications
ELISA

Description

Mouse Macrophage-stimulating protein receptor (MST1R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse MST1R concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Macrophage-stimulating protein receptor (MST1R)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.094 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q62190
Gene ID
19882
Alias
Macrophage-stimulating protein receptor,RON,SEA,PTK8,CD136,NPCA3,CDw136,MSP receptor,Protein-tyrosine kinase 8
Background
Elisa Kits for: MST1R
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Descripción

MST1R, also known as RON receptor tyrosine kinase or Macrophage-Stimulating 1 Receptor, is a member of the MET proto-oncogene family. This receptor belongs to the receptor tyrosine kinase (RTK) family and plays a crucial role in various physiological processes, particularly those involving inflammation, tissue repair, cell survival, and migration. MST1R is primarily expressed in macrophages, epithelial cells, and some immune cell types and mediates its effects through interaction with its ligand, Macrophage-Stimulating Protein (MSP). Ligand binding to MST1R activates intracellular signaling cascades, leading to cell proliferation, survival, and migration, thus influencing immune responses, tissue repair, and inflammatory responses. Research has identified the significance of MST1R in the pathology of various diseases, including cancer and fibrotic disorders, due to its ability to promote cellular processes often dysregulated in malignancy and tissue scarring. In cancer, for example, MST1R is often overexpressed or mutated, leading to enhanced tumor progression, metastasis, and treatment resistance. Consequently, MST1R has emerged as a target of interest in the development of anti-cancer therapeutics.

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