Mouse Melanoma Cell Adhesion Molecule (MCAM) Protein
221€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse Melanoma Cell Adhesion Molecule (MCAM) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067984
tested applications
WB, SDS-PAGE
Description
Mouse Melanoma Cell Adhesion Molecule (MCAM) is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Melanoma Cell Adhesion Molecule (MCAM) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Tyr224-Ile464 Tag: N-terminal His tag |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 28.0 kDa Observed MW (SDS-PAGE): 35 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8R2Y2 |
| Alias | Cell surface glycoprotein MUC18,CD146,MUC18,HEMCAM,METCAM,MelCAM,Cell surface glycoprotein P1H12,Melanoma-associated antigen A32,S-endo 1 endothelial-associated antigen |
| Background | Protein MCAM |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
The melanoma cell adhesion molecule (MCAM), also known as CD146 or MUC18, is a transmembrane glycoprotein belonging to the immunoglobulin superfamily (IgSF). MCAM was initially identified as an adhesion molecule highly expressed in melanoma cells, and since then, it has been shown to play a role in various cellular processes beyond melanoma, including angiogenesis, inflammation, and immune cell trafficking. MCAM is expressed in a variety of cell types, such as endothelial cells, smooth muscle cells, and immune cells, contributing to its diverse biological functions. Its key role in cellular adhesion makes it critical in both normal physiological processes like vascular integrity and in pathological conditions such as cancer metastasis, cardiovascular disease, and inflammation.
Related Products
APC Anti-Human CD146 Antibody(AA98)
Ver Producto
Human MCAM (Cell surface glycoprotein MUC18) ELISA Kit
Ver Producto