Mouse Nucleoporin 98 kDa (NUP98) Protein

Product specifications

Proteins and Peptides

Nucleoporin 98kDa (NUP98)

E. coli

Activity: Not tested
Sequence Fragment: Thr568-Tyr776
Tag: N-terminal His tag

Mouse

Unconjugated

Calculated MW: 26.8 kDa

Recombinant

> 95%

10 µg

50 µg

100 µg

200 µg

500 µg

Lyophilized

WB, SDS-PAGE

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

Shipped within 5-7 working days.

Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.

No

Q6PFD9

ADIR2,NUP96,NUP196,Nup98-96,Nuclear pore complex protein Nup98-Nup96, nucleoporin 96,ADAR2

Protein NUP98

RUO

THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Descripción

Nucleoporin 98 and 96 precursor (NUP98) is an important member of the nuclear pore complex, involved in the regulation of macromolecular trafficking between the nucleus and cytoplasm NUP98 is part of the larger family of nucleoporins that help maintain the structural integrity and function of the nuclear pore complex, ensuring that proteins, RNA, and ribosomal subunits are efficiently transported across the nuclear envelope NUP98, in particular, is involved in the movement of RNA molecules from the nucleus to the cytoplasm, a critical step in gene expression and protein synthesis Additionally, NUP98 plays a role in the regulation of cell division and apoptosis, where it contributes to the proper functioning of the mitotic spindle and the cell cycle Dysregulation of NUP98 has been implicated in various cancers, where it contributes to the aberrant regulation of gene expression and the disruption of nuclear-cytoplasmic communication Mutations in NUP98 are also associated with hematological disorders such as leukemia, highlighting its significance in maintaining normal cellular processes and in disease progression Its role in both structural integrity and molecular trafficking makes NUP98 essential for cellular function and overall organismal health

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Nucleoporin 98 (NUP98) Antibody

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Human Nucleoporin 98 kDa (NUP98) Protein

Human Nucleoporin 98 kDa (NUP98) is a recombinant Human protein expressed in E. coli.

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