Mouse OX-2 Membrane Glycoprotein (CD200) Protein (Active)
1118€ (100 µg)
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935106861
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name
Mouse OX-2 Membrane Glycoprotein (CD200) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx692206
tested applications
SDS-PAGE
Description
Ox-2 Membrane Glycoprotein (CD200) protein is a recombinant Mouse protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Ox-2 Membrane Glycoprotein (CD200) |
| Host | HEK293 cells |
| Assay Type | Activity: Active Sequence Fragment: Met1-Gly232 Tag: C-terminal His tag |
| Origin | Mouse |
| Observed MW | 24 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | O54901-1 |
| Alias | OX-2 membrane glycoprotein,MRC,MOX1,MOX2,OX-2,My033 |
| Background | Protein CD200 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
CD200, also known as OX-2, is a membrane glycoprotein primarily involved in immune modulation. It is a member of the immunoglobulin superfamily and is widely expressed on various cell types, including neurons, epithelial cells, endothelial cells, thymocytes, and certain immune cells like B cells, T cells, and dendritic cells. CD200 plays a critical role in maintaining immune homeostasis by binding to its receptor, CD200R, predominantly on myeloid cells and some T cells. This interaction triggers an inhibitory signaling pathway that dampens immune responses, helping to prevent overactivation of the immune system and the development of autoimmunity. CD200 is implicated in a range of physiological and pathological processes, including immune tolerance, regulation of inflammation, tumor immunity, and protection of tissues from immune-mediated damage.
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