Mouse Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) CLIA Kit

Este producto es parte de ERBB2 - erb-b2 receptor tyrosine kinase 2
Mouse Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) CLIA Kit
845€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Mouse Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) CLIA Kit
Category
CLIA Kits
Provider
Abbexa
Reference
abx493189
Tested Applications
CLIA

Description

Mouse Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
CLIA Kits
Immunogen Target
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2)
Reactivity
Mouse
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.118 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard: Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma, tissue homogenates and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
Receptor tyrosine-protein kinase erbB-2,NEU,NGL,HER2,TKR1,CD340,HER-2,VSCN2,MLN 19,MLN-19,c-ERB2,c-ERB-, HER-2/neu; p185(erbB2),Metastatic lymph node gene 19 protein,Proto-oncogene Neu,Proto-oncogene c-ErbB-2,Tyrosine kinase-type cell surface,p185erbB2 receptor HER2
Background
CLIA Kits ERBB2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES.  The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.  Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

ERBB2, also known as HER2 (human epidermal growth factor receptor 2), is a receptor tyrosine kinase that is part of the ERBB receptor family. This family consists of four closely related receptors: EGFR (ERBB1), HER2 (ERBB2), HER3 (ERBB3), and HER4 (ERBB4). These receptors play crucial roles in cellular signaling pathways regulating cell growth, differentiation, survival, and apoptosis. ERBB2 is particularly significant due to its role in breast cancer and other cancers, where its overexpression or gene amplification is associated with aggressive tumor behavior and poor prognosis. ERBB2 lacks a direct ligand-binding domain but acts as a co-receptor to enhance signaling when paired with other ERBB family members. Its importance in oncology has led to the development of therapies targeting HER2, such as monoclonal antibodies and tyrosine kinase inhibitors.

Productos relacionados

abx012001

Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody

Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody is a Mouse Monoclonal antibody against Human Receptor Tyrosine-…

Ver producto
abx012006

Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This prote…

Ver producto
abx015848

Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody

ERBB2: v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian).Th…

Ver producto