Mouse T-Cell Differentiation Antigen CD6 (CD6) Protein (Active)

Product specifications

Proteins and Peptides

T-Cell Differentiation Antigen Cd6 (CD6)

HEK293 cells

Activity: Active
Sequence Fragment: Met1-Gly396
Tag: C-terminal His tag

Mouse

42.6 kDa

Recombinant

> 90% (SDS-PAGE)

100 µg

Lyophilized

SDS-PAGE

Prior to lyophilization: Sterile PBS, pH 7.4.

Shipped within 5-15 working days.

Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.

No

Q91WN5

TP120,T-cell differentiation antigen CD6,T12

Protein CD6

RUO

THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Endotoxin Level: < 1.0 EU per µg (LAL method).

Descripción

CD6 is a type I transmembrane glycoprotein expressed on the surface of T cells, some B cells, and a subset of natural killer (NK) cells. It plays a critical role in the modulation of immune responses, particularly in T-cell activation, differentiation, and immune synapse formation. CD6 is involved in regulating the threshold of T-cell receptor (TCR) signaling and acts as a co-stimulatory receptor that modulates immune responses. CD6 is expressed in the thymus, where it is involved in T-cell development, including positive and negative selection during thymic maturation. In peripheral tissues, CD6 helps facilitate immune responses against pathogens, while maintaining immune tolerance to self-antigens. Dysregulation of CD6 signaling is implicated in a range of immune-related conditions, including autoimmune diseases, inflammatory disorders, and certain types of cancer.

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