Mouse Tumor Necrosis Factor Receptor Superfamily Member 10A / CD261 (TNFRSF10A) Protein

Este producto es parte de TNFRSF10A - TNF receptor superfamily member 10a
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208€ (10 µg)

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935106861
info@markelab.com
name
Mouse Tumor Necrosis Factor Receptor Superfamily Member 10A / CD261 (TNFRSF10A) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655386
tested applications
WB, SDS-PAGE

Description

Mouse Tumor Necrosis Factor Receptor Superfamily, Member 10A (TNFRSF10A) Protein is a recombinant Mouse protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Tumor Necrosis Factor Receptor Superfamily Member 10A / CD261 (TNFRSF10A)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Please enquire.
Tag: N-terminal His tag
Origin
Mouse
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
Alias
DR4,APO2,CD261,TRAILR1,TRAILR-1,Death receptor 4,NF-related apoptosis-inducing ligand receptor 1
Background
Protein TNFRSF10A
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Descripción

TNFRSF10A (TNF receptor superfamily member 10a), also known as TRAIL receptor 1 (TRAIL-R1) or death receptor 4 (DR4), is a member of the TNF receptor superfamily. TNFRSF10A is primarily recognized for its ability to bind to TRAIL (TNF-related apoptosis-inducing ligand), a pro-apoptotic ligand that induces cell death selectively in transformed or cancerous cells. TRAIL and its receptors are part of a critical signaling axis that regulates apoptosis, especially in response to cellular stress and immune-mediated cell targeting. The receptor is expressed on the cell surface of a variety of tissues and has been implicated in numerous physiological processes, including tumor surveillance, immune response, and inflammatory regulation. Due to its ability to mediate apoptosis in abnormal cells while sparing normal cells, TNFRSF10A has gained attention in cancer research as a therapeutic target

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