Neuregulin 2 (NRG2) Antibody
286€ (100 µl)
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935106861
info@markelab.com
name
Neuregulin 2 (NRG2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx101002
tested applications
WB
Description
Polyclonal Antibody to Neuregulin 2 (NRG2).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Neuregulin 2 (NRG2) Immunogen: abx068239 - Recombinant NRG2 (Phe101-Phe211) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 0.42 mg/ml |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O14511 |
| Gene ID | 9542 |
| OMIM | 603818 |
| Alias | DON1,HRG2,NTAK,Pro-NRG2,Pro-neuregulin-2 membrane-bound isoform,Divergent of neuregulin-1,Neural- and thymus-derived activator for ERBB kinases |
| Background | Antibody anti-NRG2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Neuregulin 2 (NRG2), though structurally similar to NRG1, displays distinct expression patterns and specialized functions. Predominantly found in the brain, NRG2 is integral to synaptic stability, neurotransmission, and neural development. By signaling through ErbB receptor pathways, NRG2 contributes to the interactions between neurons and glial cells, thus supporting neural network formation and maintenance. Research has begun to associate NRG2 with neuropsychiatric disorders, cognitive processes, and neuroplasticity. These emerging links make it a promising area for exploration in understanding the mechanisms underlying mental health conditions and potential therapeutic interventions.
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