Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
NMNAT1 Antibody is a Rabbit Polyclonal Antibody against NMNAT1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9HAN9 |
| Gene ID | 64802 |
| NCBI Accession | NP_073624.2 |
| Background | Antibody anti-NMNAT1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Related Products
Mouse NMNAT1 (NMN adenylyl transferase 1) ELISA Kit
Ver Producto
Rat NMNAT1 (Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1) ELISA Kit
Ver Producto
NMNAT1 antibody
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide(NMN) and ATP(PubMed:17402747). Can also use the deamidated form; nicotinic acid mononucleotide(NaMN) as substrate with the same efficiency(PubMed:17402747). Can use triazofurin monophosphate(TrMP) as substrate(PubMed:17402747). Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+)(PubMed:17402747). For the pyrophosphorolytic activity, prefers NAD(+) and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate(NHD) and nicotinamide guanine dinucleotide(NGD) less effectively(PubMed:17402747). Involved in the synthesis of ATP in the nucleus, together with PARP1, PARG and NUDT5(PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming(PubMed:27257257). Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+)(PubMed:17402747). Protects against axonal degeneration following mechanical or toxic insults(By similarity).
Ver Producto