Oxysterols Receptor LXR-Beta (NR1H2) Antibody
286€ (100 µl)
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935106861
info@markelab.com
name
Oxysterols Receptor LXR-Beta (NR1H2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx131382
tested applications
WB, IHC
Description
Liver X Receptor Beta Antibody is a Rabbit Polyclonal against Liver X Receptor Beta.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Oxysterols Receptor LXR-Beta (NR1H2) Immunogen: abx650300 - Recombinant LXRb (Met1-Glu446) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Mouse |
| Assay Type | Concentration: 0.38 mg/ml |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q60644 |
| Gene ID | 22260 |
| Alias | NER,UNR,LXRB,LXR-b,NER-I,RIP15,Oxysterols receptor LXR-beta,Liver X receptor beta,Nuclear receptor NER |
| Background | Antibody anti-NR1H2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Nuclear receptor subfamily 1 group H member 2 (NR1H2), also known as LXRα (liver X receptor alpha), is a nuclear receptor involved in regulating lipid metabolism, cholesterol homeostasis, and immune response NR1H2 is primarily expressed in tissues such as the liver, adipose tissue, and macrophages, where it regulates genes involved in the absorption, storage, and catabolism of cholesterol and lipids LXRα plays a key role in maintaining cholesterol balance by promoting the expression of genes that enhance cholesterol efflux and inhibit cholesterol biosynthesis It also regulates inflammatory pathways, influencing the immune system's response to atherosclerosis and other chronic inflammatory diseases Dysregulation of NR1H2 signaling has been associated with cardiovascular diseases, such as atherosclerosis, where improper lipid metabolism leads to the accumulation of cholesterol plaques in blood vessels LXRα is also a potential therapeutic target for managing metabolic diseases, inflammation, and lipid-related disorders
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Mouse Oxysterols Receptor LXR-Beta (NR1H2) Protein
Mouse LXRb Protein is a recombinant Mouse protein expressed in E. coli.
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