Pig Dihydrolipoamide Acetyltransferase Component Of Pyruvate Dehydrogenase Complex (PDHX) Protein

Este producto es parte de PDHX - Pyruvate dehydrogenase protein X
Product Graph
481€ (50 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Pig Dihydrolipoamide Acetyltransferase Component Of Pyruvate Dehydrogenase Complex (PDHX) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx659715
tested applications
WB, SDS-PAGE

Description

Pig Dihydrolipoamide Acetyltransferase Component Of Pyruvate Dehydrogenase Complex (PDHX) Protein is a recombinant Pig protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Dihydrolipoamide Acetyltransferase Component Of Pyruvate Dehydrogenase Complex (PDHX)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Pro54-Ala500
Tag: N-terminal His Tag
Origin
Pig
Conjugation
Unconjugated
Observed MW
Calculated MW: 51.6 kDa  Observed MW (SDS-PAGE): 54 kDa
Expression
Recombinant
Purity
> 95%
Size 1
50 µg
Size 2
100 µg
Size 3
200 µg
Size 4
500 µg
Size 5
1 mg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
F1SGT3
Background
Protein PDHX
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Descripción

Related Products

FNab06271

PDHX antibody

Required for anchoring dihydrolipoamide dehydrogenase(E3) to the dihydrolipoamide transacetylase(E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.

Ver Producto
P4048

Recombinant Human PDHX

Ver Producto
abx004919

Pyruvate Dehydrogenase Complex Component X (PDHX) Antibody

PDHX Antibody is a Rabbit Polyclonal antibody against PDHX. The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood. This protein is also a minor antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Ver Producto