Polyadenylate-Binding Protein 1 (PABPC1) Antibody
260€ (50 µg)
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935106861
info@markelab.com
name
Polyadenylate-Binding Protein 1 (PABPC1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx377636
tested applications
ELISA, WB, IHC
Description
Polyadenylate-Binding Protein 1 (PABPC1) Antibody is a Rabbit polyclonal antibody for the detection of Human Polyadenylate-Binding Protein 1 (PABPC1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Polyadenylate-Binding Protein 1 (PABPC1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11940 |
| Gene ID | 26986 |
| NCBI Accession | NP_002559.2 |
| Background | Antibody anti-PABPC1 |
| Status | RUO |
Descripción
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PABPC1 binds the poly (A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly (A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
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