Polycomb Complex Protein BMI-1 (BMI1) Peptide

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Description
Polycomb Complex Protein BMI-1 (BMI1) Peptide is a synthetic peptide.
Documents del producto
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Polycomb Complex Protein BMI-1 (BMI1) |
Host | Synthetic |
Recommended Dilution | BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Observed MW | Sequence Fragment: C-Terminus: C-NHQSSFANRPRKS |
Size 1 | 100 µg |
Form | Lyophilized Reconstitute in deionized water. |
Tested Applications | P-ELISA |
Buffer | Prior to lyophilization: Deionized water. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Gene ID | 648 |
NCBI Accession | NP_005171.4 |
Background | Protein BMI1 |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
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