Prolylcarboxypeptidase (PRCP) Antibody
195€ (20 µl)
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name
Prolylcarboxypeptidase (PRCP) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx002965
tested applications
ELISA, WB
Description
PRCP Antibody is a Rabbit Polyclonal antibody against PRCP. The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Prolylcarboxypeptidase (PRCP) |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P42785 |
| Gene ID | 5547 |
| NCBI Accession | NP_005031.1 |
| Background | Antibody anti-PRCP |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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PRCP antibody
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
Ver Producto