Prominin-1 (PROM1) Antibody
273€ (100 µl)
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935106861
info@markelab.com
name
Prominin-1 (PROM1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx100859
tested applications
WB, IHC
Description
Polyclonal Antibody to PROM1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Prominin-1 (PROM1) Immunogen: abx068692 - Recombinant PROM1 (Ala180-Trp435) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Mouse |
| Assay Type | Concentration: 0.49 mg/ml |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O54990 |
| Alias | RP41,AC133,CD133,MCDR2,STGD4,CORD12,PROML1,MSTP061,Prominin-like protein 1 |
| Background | Antibody anti-PROM1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Prominin-1 (PROM1), also known as CD133, is a transmembrane glycoprotein that plays a significant role in stem cell biology and cellular development. Widely recognized as a marker for stem and progenitor cells in various tissues, PROM1 is expressed on the apical surface of epithelial and hematopoietic stem cells. It participates in cellular differentiation and is crucial for maintaining the stem cell niche, with implications in tissue regeneration and repair. PROM1 has become a focus of research due to its role in cell signaling and its involvement in numerous developmental pathways, including those of the nervous system, retina, and digestive tract. Additionally, aberrant PROM1 expression is associated with cancer, specifically in cancer stem cells, and its presence is often used as a marker to identify cells with tumorigenic potential. PROM1’s relevance to cellular organization and tissue homeostasis, along with its association with pathological conditions, makes it an important molecule in cell biology and oncology.
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Mouse Prominin-1 (PROM1) Protein
Mouse PROM1 is a recombinant Mouse protein expressed in E. coli.
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