Prostate-Specific Antigen / PSA (KLK3) Antibody

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195€ (20 µl)

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935106861
info@markelab.com
name
Prostate-Specific Antigen / PSA (KLK3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001669
tested applications
ELISA, WB, IHC, IF/ICC, IP

Description

KLK3 Antibody is a Rabbit Polyclonal antibody against KLK3. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Prostate-Specific Antigen / PSA (KLK3)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC, IP
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P07288
Gene ID
354
NCBI Accession
NP_001639.1
OMIM
176820
Background
Antibody anti-KLK3
Status
RUO
Note
Concentration: > 0.2 mg/ml -

Descripción

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