Proteasome Subunit Alpha Type 3 (PSMA3) Antibody

Product Graph
195€ (20 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Proteasome Subunit Alpha Type 3 (PSMA3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001157
tested applications
ELISA, WB, IHC, IF/ICC, IP

Description

PSMA3 Antibody is a Rabbit Polyclonal antibody against PSMA3. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Proteasome Subunit Alpha Type 3 (PSMA3)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/100 - 1/500, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC, IP
Buffer
PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P25788
Gene ID
5684
NCBI Accession
NP_002779.1
Background
Antibody anti-PSMA3
Status
RUO
Note
Concentration: > 0.2 mg/ml -

Descripción

Related Products

FNab06863

PSMA3 antibody

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor(TBXA2R) isoform 2.

Ver Producto
P4979

Recombinant Human PSMA3

Ver Producto
P9094

Recombinant Human PSMA3

Ver Producto