Rat Archaelysin Family Metallopeptidase 1 (AMZ1) ELISA Kit
715€ (96 tests)
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name
Rat Archaelysin Family Metallopeptidase 1 (AMZ1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501679
tested applications
ELISA
Description
Rat Archaelysin Family Metallopeptidase 1 (AMZ1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Archaemetzincin-1 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Archaelysin Family Metallopeptidase 1 (AMZ1) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q400C9 |
| Alias | AMZ1 |
| Background | Elisa Kits for: AMZ1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
AMZ1 is a member of the archaelysin family of zinc-dependent metallopeptidases, enzymes that cleave peptide bonds in a variety of substrates. AMZ1 is expressed in multiple tissues, where it functions in protein turnover, extracellular matrix remodeling, and cellular signaling. As a metallopeptidase, AMZ1 requires a zinc ion for catalytic activity, which stabilizes the enzyme's active site and facilitates hydrolysis of peptide bonds. AMZ1 is thought to participate in processes such as tissue development, wound healing, and immune responses by regulating extracellular matrix components and growth factors. Dysregulation of AMZ1 activity has been implicated in pathological processes such as fibrosis, inflammation, and tumor progression, where excessive matrix degradation or improper protease activity contributes to disease. AMZ1's ability to cleave a broad range of substrates highlights its importance in maintaining proteolytic balance, tissue homeostasis, and intercellular communication.
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AMZ1 antibody
AMZ1, also named as KIAA1950, is a new human Zinc metalloproteases. It exhibits aminopeptidase activity against neurogranin in vitro. AMZ1 does not hydrolyze angiotensin-2. It is mainly detected in liver and heart. AMZ1 has some isoforms with MW 55 kDa, 33 kDa, 30 kDa and 28 kDa.
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