Rat CASP8 And FADD Like Apoptosis Regulator (CFLAR) Protein
247€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Rat CASP8 And FADD Like Apoptosis Regulator (CFLAR) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx168536
Tested Applications
WB, SDS-PAGE
Description
Rat CASP8 And FADD Like Apoptosis Regulator Protein is a recombinant Rat protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | CASP8 And FADD Like Apoptosis Regulator (CFLAR) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Arg43-Tyr281 Tag: N-terminal His tag |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 31.2 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CASP8 and FADD like apoptosis regulator, cFLIP |
| Background | Protein CFLAR |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
CASP8 and FADD-like apoptosis regulator (CFLAR), also known as c-FLIP, is an important regulatory protein that modulates apoptosis, particularly in response to death receptor signaling. CFLAR is structurally related to the caspase family but lacks protease activity, allowing it to inhibit caspase-8 activation in the death receptor pathway. By binding to the death-inducing signaling complex (DISC), CFLAR blocks the activation of downstream apoptotic signaling, effectively acting as an inhibitor of apoptosis. This inhibition allows cells to evade cell death, and as such, CFLAR has been implicated in promoting cell survival in various cancers, as well as playing a role in immune responses.
Productos relacionados
CASP8 And FADD Like Apoptosis Regulator (CFLAR) Antibody
CFLAR Antibody is a Rabbit Polyclonal antibody against CFLAR. The protein encoded by this gene is a regulator of apoptos…
Ver producto
CASP8 And FADD Like Apoptosis Regulator (CFLAR) Antibody
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8.However, the encod…
Ver producto
CASP8 And FADD Like Apoptosis Regulator (CFLAR) Antibody
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8.However, the encod…
Ver producto