Rat Bdnf / Nt-3 Growth Factors Receptor (NTRK2) Protein (Active)
624€ (20 µg)
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935106861
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name
Rat Bdnf / Nt-3 Growth Factors Receptor (NTRK2) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx692454
tested applications
SDS-PAGE
Description
Bdnf / Nt-3 Growth Factors Receptor (NTRK2) protein is a recombinant Rat protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Bdnf / Nt-3 Growth Factors Receptor (NTRK2) |
| Host | HEK293 cells |
| Assay Type | Activity: Active Sequence Fragment: Met1-His429 Tag: C-terminal His tag |
| Origin | Rat |
| Observed MW | 47.1 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 20 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q63604-2 |
| Alias | OBHD,TRKB,DEE58,trk-B,EIEE58,GP145-TrkB,Tropomyosin-related kinase B,TrkB tyrosine kinase,Neurotrophic tyrosine kinase receptor type 2,BDNF/NT-3 growth factors receptor |
| Background | Protein NTRK2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
Neurotrophic receptor tyrosine kinase 2 (NTRK2), often referred to as TrkB, interacts specifically with brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5). This receptor is central to processes like neuroplasticity, synaptic strength regulation, and long-term potentiation—mechanisms foundational for cognitive functions such as learning and memory. In addition to its role in brain health, NTRK2 is involved in mood regulation, and aberrations in its signaling pathways are associated with neuropsychiatric disorders, including depression, anxiety, and schizophrenia, emphasizing its role in mental health research and therapeutic interventions.
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