Rat Interleukin-13 Receptor Subunit Alpha-1 (IL13RA1) Protein
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Description
Interleukin-13 Receptor Subunit Alpha-1 (IL13RA1) protein is a recombinant Rat protein expressed in HEK293 cells.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin-13 Receptor Subunit Alpha-1 (IL13RA1) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Thr342 Tag: C-terminal Fc tag |
| Origin | Rat |
| Observed MW | 62.9 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q561K3 |
| Alias | IL-13 receptor subunit alpha-1,NR4,CT19,CD213A1,IL-13Ra,IL-13R subunit alpha-1 |
| Background | Protein IL13Ra1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
Interleukin-13 receptor subunit alpha-1 (IL13RA1) is a protein that serves as a primary component of the interleukin-13 receptor (IL-13R) complex, a receptor essential for immune regulation and inflammatory responses. IL13RA1, encoded by the IL13RA1 gene, is a type I cytokine receptor that primarily binds to the cytokine interleukin-13 (IL-13), a cytokine associated with type 2 helper T cell (Th2) immune responses. IL13RA1 also participates in binding interleukin-4 (IL-4), a cytokine closely related to IL-13 in function and structure, by forming a complex with IL-4 receptor alpha (IL4RA). IL13RA1’s function in the immune system is particularly significant in responses to allergens, where it helps mediate the characteristic responses associated with allergic asthma, atopic dermatitis, and allergic rhinitis. Beyond allergy and inflammation, IL13RA1’s signaling pathways are implicated in fibrotic diseases and certain cancers, as IL-13 and IL-4 promote tissue remodeling, fibrosis, and immune modulation.
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