Rat Opioid Receptor Delta 1 (OPRD1) ELISA Kit

Este producto es parte de OPR - Opioid Receptor
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715€ (96 tests)

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935106861
info@markelab.com
name
Rat Opioid Receptor Delta 1 (OPRD1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx536896
tested applications
ELISA

Description

Rat Opioid Receptor Delta 1 (OPRD1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Delta-type opioid receptor concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Opioid Receptor Delta 1 (OPRD1)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P33533
Alias
OPRD1,DOP,DOR,OP1,Delta receptor,DOR-1,DOPr,opioid receptor,OPRD
Background
Elisa Kits for: OPRD1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Descripción

OPRD1, also known as the delta-opioid receptor, is a G protein-coupled receptor (GPCR) activated by endogenous opioid peptides such as enkephalins. It is expressed in the central nervous system (CNS), including the cortex, limbic system, and spinal cord, where it modulates pain perception, mood regulation, and neuroprotection. OPRD1 couples to Gi/o proteins, inhibiting adenylate cyclase activity, reducing cAMP levels, and modulating ion channel activity to decrease neuronal excitability. Activation of OPRD1 produces analgesic effects, particularly in chronic and neuropathic pain conditions. It is also involved in regulating mood and emotional behaviors, with potential roles in reducing anxiety and depressive symptoms. Dysregulation of OPRD1 has been linked to pain disorders, addiction, and mood dysregulation. Selective OPRD1 agonists are being explored for their analgesic properties with lower addiction potential compared to mu-opioid receptor agonists. OPRD1 modulation represents a promising therapeutic approach for pain management, mood disorders, and neuroprotection.

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