Rat Protein Phosphatase, Mg2+/Mn2+ Dependent 1F (PPM1F) ELISA Kit

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715€ (96 tests)

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935106861
info@markelab.com
name
Rat Protein Phosphatase, Mg2+/Mn2+ Dependent 1F (PPM1F) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx539784
tested applications
ELISA

Description

Rat Protein Phosphatase, Mg2+/Mn2+ Dependent 1F (PPM1F) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Protein phosphatase 1F concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Protein Phosphatase, Mg2+/Mn2+ Dependent 1F (PPM1F)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9WVR7
Background
Elisa kits for PPM1F
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

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The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.

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