Recombinant Human KLHL12
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Host | E.Coli |
| Reactivity | Human |
| Assay Data | Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex. |
| Recommended Dilution | ¥ |
| Isotype | ¥ |
| Clone ID | ¥ |
| Observed MW | 62.4 kDa |
| Expression | 1-568 |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Size 1 | 50μg |
| Size 2 | 200μg |
| Size 3 | 1mg |
| Form | Lyophilized powder |
| Tested Applications | Western Blot, ELISA |
| Buffer | Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5% trehalose, pH 7.4. |
| Availability | 7 days |
| Storage | The lyophilized protein is stable at -20 °C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 °C for 3 months or 1 week at 2 to 8 °C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle. |
| UniProt ID | Q53G59 |
| Alias | C3IP1, CUL3 interacting protein 1, CUL3-interacting protein 1, DKIR, DKIR homolog, FLJ27152, hDKIR, Kelch like 12, Kelch like 12 (Drosophila), Kelch like 12 variant, Kelch like protein 12, Kelch like protein C3IP1, kelch-like family member 12, Kelch-like protein 12, KLH12_HUMAN, KLHL 12, klhl12, OTTHUMP00000038799 |
| Background | Protein KLHL12 |
| Status | RUO |
| Note | Tag : N-terminal His Tag |
Related Products
Human Anti-KLHL12 (anti-Kelch-like protein 12 antibody) ELISA Kit
Ver Producto
Human KLHL12 (Kelch-like protein 12) ELISA Kit
Ver Producto
KLHL12 antibody
Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem(ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31(SEC31A or SEC31B). As part of the BCR(KLHL12) complex, also acts as a negative regulator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3. The BCR(KLHL12) complex also mediates polyubiquitination of DRD4, without leading to degradation of DRD4.
Ver Producto