Recombinant Mouse CNDP2
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Product specifications
| Category | Proteins and Peptides |
| Host | Mammalian Cells |
| Reactivity | Mouse |
| Observed MW | 56-60 kDa |
| Expression | Met1-Asn475 |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| Size 1 | 10μg |
| Size 2 | 50μg |
| Size 3 | 500μg |
| Size 4 | 1mg |
| Form | Liquid |
| Tested Applications | Western Blot, ELISA |
| Buffer | 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, 10% Glycerol, pH 8.0. |
| Availability | 7 days |
| Storage | The protein solution is stable at -80°C for 6 months after receipt, and for 3 months under sterile conditions after opening. Avoid repeated freeze/thaw cycle. |
| UniProt ID | Q9D1A2 |
| Alias | CNDP2,CNDP dipeptidase 2,Cytosolic non-specific dipeptidase,Glutamate carboxypeptidase-like protein 1,Cn2 |
| Background | Protein CNDP2 |
| Status | RUO |
| Note | Endotoxin: < 1 EU/µg as determined by LAL test. Tag : C-terminal His Tag |
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CNDP2 antibody
Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly(PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase(MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation(PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma(HCC) cells(PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis(PubMed:25964343).
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