Ring Finger Protein 144B (RNF144B) Antibody
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Description
RNF144B Antibody is a Rabbit Polyclonal against RNF144B.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ring Finger Protein 144B (RNF144B) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/40000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7Z419 |
| Gene ID | 255488 |
| Background | Antibody anti-RNF144B |
| Status | RUO |
Descripción
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Ring Finger Protein 144B (RNF144B) Antibody
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.
Ver Producto
Ring Finger Protein 144B (RNF144B) Antibody
RNF144B Antibody is a Rabbit Polyclonal against RNF144B.
Ver ProductoRing Finger Protein 144B (RNF144B) Antibody
RNF144B Antibody is a Rabbit Polyclonal against RNF144B.
Ver Producto