Semaphorin 3C (SEMA3C) Antibody
377€ (100 µg)
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935106861
info@markelab.com
name
Semaphorin 3C (SEMA3C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx237706
tested applications
ELISA, WB
Description
SEMA3C Antibody is a Rabbit Polyclonal against SEMA3C.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Semaphorin 3C (SEMA3C) Immunogen: sema domain, immunoglobulin domain(Ig), short basic domain, secreted,(semaphorin) 3C |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 70 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99985 |
| Gene ID | 10512 |
| OMIM | 602645 |
| Alias | SemE,SEMAE,Semaphorin-E |
| Background | Antibody anti-SEMA3C |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
SEMA3C (Semaphorin 3C) is another key member of the class 3 semaphorins, primarily involved in neuronal pathfinding, cardiovascular development, and cancer biology. SEMA3C signals through neuropilin-2 (NRP2) and plexin receptors to regulate cellular behaviors such as migration, invasion, and adhesion. In cancer, SEMA3C is frequently upregulated, where it promotes tumor growth and metastasis by facilitating angiogenesis and modulating the tumor microenvironment. Its dual roles in development and oncogenesis make it a compelling target for both regenerative medicine and oncology.
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