Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) Antibody
286€ (100 µl)
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935106861
info@markelab.com
name
Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx104186
tested applications
WB
Description
Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) Immunogen: SIGLEC10 (Met571-Gln697) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96LC7 |
| Alias | SLG2,PRO940,SIGLEC-10,Siglec-like protein 2 |
| Background | Antibody anti-SIGLEC10 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
SIGLEC10 is a transmembrane protein expressed on various immune cells, including B cells, macrophages, and dendritic cells. It recognizes sialic acid-containing ligands and is known for its inhibitory role in immune responses, mediated through immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail. SIGLEC10 is implicated in preventing excessive inflammation and maintaining immune tolerance.
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