SLAM Family Member 6 (SLAMF6) Antibody

Este producto es parte de SLAMF6 - SLAM family member 6
Product Graph
312€ (50 µg)

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935106861
info@markelab.com
name
SLAM Family Member 6 (SLAMF6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx421799
tested applications
FCM

Description

SLAM Family Member 6 (SLAMF6) Antibody is a Mouse Monoclonal antibody for the detection of SLAM Family Member 6 (SLAMF6) in Human samples.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Target: SLAM Family Member 6 (SLAMF6)
Host
Mouse
Reactivity
Human
Assay Type
Concentration: 1 mg/ml
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1 Kappa
Clone ID
Y727
Purity
> 95% (SDS-PAGE)
Purification
Purified by Protein A/G affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
FCM
Buffer
0.01 M PBS, pH 7.4, 0.09% Sodium azide.
Availability
Shipped within 5-12 working days.
Storage
Store at 4°C if the entire vial will be used within 1 week. Aliquot and store at -20°C or -80°C for long-term storage. Avoid repeated freeze-thaw cycles.
Dry Ice
No
UniProt ID
Q96DU3
Gene ID
114836
NCBI Accession
NP_001171643.1
Alias
Activating NK receptor,KALI,NTBA,CD352,KALIb,Ly108,NTB-A,SF2000,NK-T-B-antigen
Background
Antibody anti-SLAMF6
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

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The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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