T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody
65€ (25 µg)
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935106861
info@markelab.com
name
T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx228069
tested applications
IHC, IF/ICC, FCM, IP
Description
CD86 antibody is a Rat monoclonal antibody against CD86.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Size 1 | 25 µg |
| Size 2 | 100 µg |
| Size 3 | 1 mg |
| Tested Applications | IHC, IF/ICC, FCM, IP |
| Buffer | PBS with 0.05% Proclin300. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P42082 |
| Gene ID | 12524 |
| Alias | B7,BB1,B7-1,B7.1,LAB7,CD28LG,CD28LG1,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1,T-lymphocyte activation antigen CD80 |
| Background | Antibody anti-CD80 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
CD80, also known as B7-1, is a protein encoded by the CD80 gene in humans. It is an essential costimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, B cells, and macrophages. CD80 plays a critical role in the regulation of immune responses by providing the necessary second signal for T cell activation and survival. This molecule interacts with CD28 and CTLA-4 receptors on T cells, mediating various immune responses. The discovery and understanding of CD80 have significant implications for immunology, particularly in the context of autoimmune diseases, transplant rejection, and cancer immunotherapy.
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