Topoisomerase (DNA) II Alpha (TOP2A) Antibody
312€ (60 µl)
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name
Topoisomerase (DNA) II Alpha (TOP2A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx000841
tested applications
WB
Description
TOP2A Antibody is a Rabbit Polyclonal antibody against TOP2A. TOP2A, also named as TOP2, belongs to the type II topoisomerase family. Topoisomerase II makes double-strand breaks. TOP2 control the topological states of DNA by transient breakage and subsequent rejoining of DNA strands. The antibody is specific to the gene TOP2A.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Topoisomerase (DNA) II Alpha (TOP2A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11388 |
| Gene ID | 7153 |
| NCBI Accession | NP_001058.2 |
| Background | Antibody anti-TOP2A |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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TOP2A antibody
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation(By similarity).
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