TP53-Regulated Inhibitor of Apoptosis 1 (TRIAP1) Antibody
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Description
TRIAP1 Antibody is a Rabbit Polyclonal antibody against TRIAP1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | TP53-Regulated Inhibitor of Apoptosis 1 (TRIAP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43715 |
| Gene ID | 51499 |
| NCBI Accession | NP_057483.1 |
| Background | Antibody anti-TRIAP1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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Human TRIAP1 (TP53-regulated inhibitor of apoptosis 1) ELISA Kit
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TRIAP1 antibody
Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane(PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid(PA) between liposomes(in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space(in vivo)(PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis(PubMed:15735003).
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