Transcription Factor Jun Phospho-Ser243 (Jun pS243) Antibody
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Description
Transcription Factor Jun Phospho-Ser243 (Jun pS243) Antibody is a rabbit polyclonal antibody against Transcription Factor Jun Phospho-Ser243 (Jun pS243). Immunogen region is Internal. Specificity is as follows for the reactive species: H:S243, M:S246, R:S246.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Transcription Factor Jun Phospho-Ser243 (Jun pS243) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Data | Modification: Phosphorylation // Target Modification: Ser243 |
| Recommended Dilution | WB: 1/500 - 1/3000, IHC: 1/50 - 1/100, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P05412 |
| Background | Antibody anti-JUN |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer(CRC) cells(PubMed:24623306). Binds to the USP28 promoter in colorectal cancer(CRC) cells(PubMed:24623306).
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Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer(CRC) cells(PubMed:24623306). Binds to the USP28 promoter in colorectal cancer(CRC) cells(PubMed:24623306).
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