Transforming Growth Factor Beta-3 Proprotein (TGFB3) Antibody
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Description
Transforming Growth Factor Beta-3 Proprotein (TGFB3) Antibody is a Rabbit polyclonal antibody for the detection of Human, Mouse Transforming Growth Factor Beta-3 Proprotein (TGFB3).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Transforming Growth Factor Beta-3 Proprotein (TGFB3) Immunogen: Recombinant Transforming Growth Factor Beta-3 Proprotein (Ala301-Ser412) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P10600 |
| Gene ID | 7043 |
| NCBI Accession | NP_001316867.1 |
| Alias | ARVD,ARVD1,LDS5,RNHF,TGF-beta3,Latency-associated peptide LAP,Transforming growth factor beta-3 |
| Background | Antibody anti-TGFB3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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TGFB3 antibody
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1.
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