Transforming Growth Factor Beta-3 Proprotein (TGFB3) Antibody
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Description
Transforming Growth Factor Beta-3 Proprotein (TGFB3) Antibody is a Mouse Monoclonal antibody for the detection of Transforming Growth Factor Beta-3 Proprotein (TGFB3) in Human samples.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Transforming Growth Factor Beta-3 Proprotein (TGFB3) |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a Kappa |
| Clone ID | R583 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, FCM |
| Buffer | 0.01 M PBS, pH 7.4, 0.09% Sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4°C if the entire vial will be used within 1 week. Aliquot and store at -20°C or -80°C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | P10600 |
| Gene ID | 7043 |
| NCBI Accession | NP_001316867.1 |
| Alias | ARVD,ARVD1,LDS5,RNHF,TGF-beta3,Latency-associated peptide LAP,Transforming growth factor beta-3 |
| Background | Antibody anti-TGFB3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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TGFB3 antibody
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1.
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