Tripeptidyl Peptidase I (TPP1) Antibody
195€ (20 µl)
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935106861
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name
Tripeptidyl Peptidase I (TPP1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx004302
tested applications
ELISA, WB
Description
TPP1 Antibody is a Rabbit Polyclonal antibody against TPP1. This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Tripeptidyl Peptidase I (TPP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O14773 |
| Gene ID | 1200 |
| NCBI Accession | NP_000382.3 |
| Background | Antibody anti-TPP1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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Human TPP1 (Tripeptidyl-peptidase 1) ELISA Kit
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TPP1 antibody
Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus(By similarity).
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