Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Antibody
273€ (100 µl)
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935106861
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name
Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx104670
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Immunogen: abx069561 - Recombinant TNFRSF17 (Leu71-Thr184) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O88472 |
| Alias | Tumor necrosis factor receptor superfamily member 17,BCM,BCMA,CD269,TNFRSF13A,B-cell maturation protein |
| Background | Antibody anti-TNFRSF17 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
TNFRSF17, also known as B-cell maturation antigen (BCMA), is a receptor within the tumor necrosis factor receptor superfamily (TNFRSF). It is primarily expressed on B cells, specifically on mature and plasma B cells, where it plays a pivotal role in B cell survival, differentiation, and immunoglobulin secretion. TNFRSF17 is unique among TNFRSF members because of its specificity for binding ligands like APRIL (A Proliferation-Inducing Ligand) and BAFF (B-cell Activating Factor), which are members of the TNF ligand superfamily. BCMA is essential for maintaining long-lived plasma cells and for regulating immune responses, particularly in the context of adaptive immunity. TNFRSF17, also known as B-cell maturation antigen (BCMA), is a receptor within the tumor necrosis factor receptor superfamily (TNFRSF). It is primarily expressed on B cells, specifically on mature and plasma B cells, where it plays a pivotal role in B cell survival, differentiation, and immunoglobulin secretion. TNFRSF17 is unique among TNFRSF members because of its specificity for binding ligands like APRIL (A Proliferation-Inducing Ligand) and BAFF (B-cell Activating Factor), which are members of the TNF ligand superfamily. BCMA is essential for maintaining long-lived plasma cells and for regulating immune responses, particularly in the context of adaptive immunity.
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