14-3-3 Protein Eta (YWHAH) Antibody
312€ (60 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
14-3-3 Protein Eta (YWHAH) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx123576
Tested Applications
WB, IF/ICC
Description
14-3-3 Protein Eta (YWHAH) Antibody is a Rabbit Polyclonal against 14-3-3 eta.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: 14-3-3 Protein Eta (YWHAH) Immunogen: Recombinant fusion protein corresponding to human YWHAH |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 28 kDa Observed MW: 28 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q04917 |
| Gene ID | 7533 |
| NCBI Accession | NP_003396.1 |
| Alias | YWHAH, YWHA1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta |
| Background | Antibody anti-YWHAH |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
YWHAH, a member of the 14-3-3 protein family, acts as an adaptor molecule that binds phosphorylated serine/threonine residues on target proteins, regulating their stability, localization, and function. YWHAH is highly expressed in the brain, where it is involved in synaptic plasticity, neurotransmitter release, and neuronal development. It interacts with key signaling molecules in pathways such as MAPK, PI3K/Akt, and dopamine receptor signaling, influencing cellular processes like survival, growth, and stress response. Dysregulation of YWHAH is associated with neurological disorders such as schizophrenia, Parkinson’s disease, and rheumatoid arthritis, where altered signaling contributes to disease pathogenesis. Elevated levels of YWHAH have been detected in autoimmune diseases, highlighting its role as a biomarker. Knockout studies demonstrate impaired synaptic transmission, defects in neuronal signaling, and altered stress adaptation, emphasizing its importance in brain function, neurodevelopment, and immune regulation.
Productos relacionados
14-3-3 Protein Eta (YWHAH) Antibody
Rabbit polyclonal antibody against 14-3-3 Protein Eta (YWHAH). Immunogen region is Internal.…
Ver producto
Human 14-3-3 Protein Eta (YWHAH) Protein
Human 14-3-3 Protein Eta (YWHAH) Protein is a recombinant protein kinase.…
Ver producto
14-3-3 Protein Eta (YWHAH) Antibody (Biotin)
14-3-3 Protein Eta (YWHAH) Antibody (Biotin) is a Rabbit Polyclonal antibody against 14-3-3 protein eta conjugated to Bi…
Ver producto