ADAM Metallopeptidase Domain 2 (ADAM2) Antibody
377€ (100 µg)
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Name
ADAM Metallopeptidase Domain 2 (ADAM2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx230141
Tested Applications
ELISA, WB
Description
ADAM2 Antibody is a Rabbit Polyclonal against ADAM2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: ADAM Metallopeptidase Domain 2 (ADAM2) Immunogen: ADAM metallopeptidase domain 2 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 65-75 kDa, 100 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99965 |
| Gene ID | 2515 |
| OMIM | 601533 |
| Alias | fertilin β, fertilin beta,PH30,CT15 ,CRYN1,CRYN2,ADA,-2 |
| Background | Antibody anti-ADAM2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADAM2, also known as ADAM metallopeptidase domain 2, belongs to the ADAM (a disintegrin and metalloproteinase) family of proteins, which are involved in various biological processes such as cell adhesion, fusion, migration, and proteolysis. ADAM2 is specifically implicated in sperm-egg binding. Research on ADAM2 and related proteins has provided valuable insights into the intricate mechanisms governing fertilization. Understanding the role of ADAM2 in sperm-egg interaction has led to the development of potential diagnostic tools for assessing male fertility and identifying causes of infertility. Furthermore, ADAM2 and other members of the ADAM family are being investigated as potential targets for contraceptive development. By targeting proteins involved in sperm-egg binding and fusion, researchers aim to develop contraceptives that specifically inhibit fertilization while minimizing side effects.ADAM2 has also been implicated in other biological processes, including cell adhesion and signaling. Dysregulation of ADAM2 expression or function may contribute to various diseases and conditions beyond infertility, although further research is needed to fully elucidate its broader physiological significance.
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