Adenosine Deaminase Domain Containing Protein 2 (ADAD2) Antibody
377€ (100 µg)
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935106861
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name
Adenosine Deaminase Domain Containing Protein 2 (ADAD2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230136
tested applications
ELISA, WB
Description
ADAD2 Antibody is a Rabbit Polyclonal against ADAD2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenosine Deaminase Domain Containing Protein 2 (ADAD2) Immunogen: adenosine deaminase domain containing 2 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 62 kDa, 71 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NCV1 |
| Gene ID | 161931 |
| Alias | Testis nuclear RNA-binding protein-like |
| Background | Antibody anti-ADAD2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ADAD2 is another testis-specific protein within the adenosine deaminase domain-containing family, contributing to RNA metabolism during male germ cell development. It is involved in RNA binding and is hypothesized to regulate mRNA stability and translation during spermatogenesis. ADAD2 plays a key role in supporting the differentiation of spermatocytes and the formation of mature sperm cells. Like ADAD1, ADAD2 contains a conserved adenosine deaminase domain but does not exhibit classical enzymatic activity, suggesting its primary role lies in RNA binding and post-transcriptional regulation. Alterations in ADAD2 expression have been associated with defects in spermatogenesis and reduced male fertility. Its restricted expression pattern highlights its critical role in the development of the male reproductive system and the maintenance of germ cell integrity.
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