ATIC antibody

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935106861
info@markelab.com
name
ATIC antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00681
tested applications
ELISA, WB, IF

Description

Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis. 


Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization(PubMed:25687571).

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1:200-1:1000; IF: 1:10-1:100
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
65 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P31939
Gene ID
471
Alias
Bifunctional purine biosynthesis protein ATIC,AICAR transformylase/inosine monophosphate cyclohydrolase (ATIC),Bifunctional purine biosynthesis protein ATIC, N-terminally processed,ATIC,PURH
Background
Antibody anti-ATIC
Status
RUO
Note
Mol. Weight 65 kDa

Descripción

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ATIC antibody

Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis. Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization(PubMed:25687571).

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Bifunctional Purine Biosynthesis Protein PURH (ATIC) Antibody

ATIC Antibody is a Rabbit Polyclonal antibody against ATIC. This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.

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