BANP antibody
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935106861
info@markelab.com
name
BANP antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00799
tested applications
ELISA, IHC, WB
Description
Controls V(D)J recombination during T-cell development by repressing T-cell receptor(TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta(S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | BTG3 associated nuclear protein (BANP) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:1000; IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 56kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8N9N5 |
| Gene ID | 54971 |
| Alias | Protein BANP,BEN domain-containing protein 1,Btg3-associated nuclear protein,Scaffold/matrix-associated region-1-binding protein,BANP,BEND1,SMAR1 |
| Background | Antibody anti-BANP |
| Status | RUO |
| Note | Mol. Weight 56 kDa |
Descripción
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