CACNA1B antibody
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Description
Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated'(HVA) group and are blocked by omega-conotoxin-GVIA(omega-CTx-GVIA) and by omega-agatoxin-IIIA(omega-Aga-IIIA). They are however insensitive to dihydropyridines(DHP), and omega-agatoxin-IVA(omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | calcium channel, voltage-dependent, N type, alpha 1B subunit (CACNA1B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:1000; IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 262 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q00975 |
| Gene ID | 774 |
| Alias | Voltage-dependent N-type calcium channel subunit alpha-1B,Brain calcium channel III (BIII),Calcium channel, L type, alpha-1 polypeptide isoform 5,Voltage-gated calcium channel subunit alpha Cav2.2,CACNA1B,CACH5,CACNL1A5 |
| Background | Antibody anti-CACNA1B |
| Status | RUO |
| Note | Mol. Weight 262 kDa |
Descripción
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