CCDC40 antibody

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935106861
info@markelab.com
name
CCDC40 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01355
tested applications
ELISA, WB
Description
Required for assembly of dynein regulatory complex(DRC) and inner dynein arm(IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella(PubMed:21131974). Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer(nm) repeat length and arrangements of components in cilia and flagella(By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39(PubMed:21131974).
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | coiled-coil domain containing 40 (CCDC40) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1:500-1:2000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 90-100 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q4G0X9 |
Gene ID | 55036 |
Alias | Coiled-coil domain-containing protein 40,CCDC40,KIAA1640 |
Background | Antibody anti-CCDC40 |
Status | RUO |
Note | Mol. Weight 90-100 kDa |
Descripción
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Required for assembly of dynein regulatory complex(DRC) and inner dynein arm(IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella(PubMed:21131974). Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer(nm) repeat length and arrangements of components in cilia and flagella(By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39(PubMed:21131974).
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