CYP24A1 antibody

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935106861
info@markelab.com
name
CYP24A1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02151
tested applications
ELISA, WB, IHC
Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1, 25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | cytochrome P450, family 24, subfamily A, polypeptide 1 (CYP24A1) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 59 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q07973 |
Gene ID | 1591 |
Alias | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (24-OHase, Vitamin D(3) 24-hydroxylase),Cytochrome P450 24A1,Cytochrome P450-CC24,CYP24A1,CYP24 |
Background | Antibody anti-CYP24A1 |
Status | RUO |
Note | Mol. Weight 59 kDa |
Descripción
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CYP24A1 antibody
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1, 25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Ver Producto